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Published Resources Details Journal Article
- Title
- A "naturally-occurring" anti-E which distinguishes a variant of the E antigen in Australian aborigines
- In
- Vox Sanguinis
- Imprint
- vol. 7, 1962, pp. 22-32
- Url
- http://doi.org/10.1111/j.1423-0410.1962.tb03225.x
- Abstract
A serum from a 70 year old male Australian aborigine is described which reacts only with enzyme-treated cells carrying the E antigen. The serum reacts strongly with all E-positive cells from Caucasian whites, but fails to react with a large number of E-positive cells from Australian aborigines. Gene frequency analysis and family studies suggest that the E antigen is complex. Caucasian whites are antigenically all E+ET, whereas Australian aborigines may be homozygous E + ET, heterozygous E+ET/E + Et or homozygous E + Et/E + Et. The aboriginal serum studied is a "naturally-occurring" anti-ET. Preliminary evidence suggests that anti-E sera of immune origin from Caucasian whites are principally anti-E + ET.
PMID:
13926799
[PubMed - indexed for MEDLINE]
Related Archival resources
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- Correspondence, Draft Manuscript and Maps of family relationships, 1960 - 1962, 04B-12; National Centre for Indigenous Genomics. Details
